Getting My Promethazine codeine syrup To Work
Getting My Promethazine codeine syrup To Work
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Promethazine HCl and Codeine Phosphate Oral Solution must be utilised with caution in individuals with impairment of hepatic functionality, and patients should be monitored closely for respiratory depression, sedation, and hypotension.
Get health-related support at once if you observe any of the next: sluggish/shallow respiratory, severe drowsiness/trouble waking up, confusion.
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Promethazine is contraindicated in comatose states, and in individuals known to be hypersensitive or to possess had an idiosyncratic reaction to promethazine or to other phenothiazines.
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Lactation No less than a person Dying was documented inside a nursing infant who was exposed to higher amounts of morphine in breast milk because the mom was an ultra-fast metabolizer of codeine.
, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer for instance rifampin, carbamazepine, and phenytoin, may end in an increase in codeine plasma concentrations with subsequently better metabolism by cytochrome P450 2D6, leading to greater morphine amounts, which could raise or lengthen adverse reactions and will trigger potentially lethal respiratory depression.
In case the response to an opioid antagonist is suboptimal or only transient in mother nature, administer additional antagonist as directed because of Promethazine codeine syrup the solution’s prescribing information and facts. The respiratory depressant effects of promethazine are certainly not reversed by opioid antagonists, such as naloxone.
Acquire this medication by mouth with or with out foods as directed by your health practitioner, commonly every 4 to six hrs as essential. Since dosing recommendations may perhaps fluctuate, cautiously observe your physician's directions for taking this medication.
Unwanted effects that sometimes don't need clinical awareness (report to your treatment team if they proceed or are bothersome):
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This medication might cause you to much more delicate on the Solar. Limit your time during the sun. Stay away from tanning booths and sunlamps. Use sunscreen and use protecting clothes when outside. Convey to your doctor right away if you will get sunburned or have pores and skin blisters/redness.
Promethazine and codeine may well lead to marked drowsiness or might impair the mental and/or Bodily talents required to the effectiveness of probably harmful tasks, which include driving a auto or functioning machinery.
To scale back the chance of dizziness and lightheadedness, stand up gradually when increasing from a sitting or lying placement.